I studied for 8 years organometallic chemistry, catalysis and cross-coupling reactions under the supervision of outstanding mentors : undergraduate project in the lab of Paul Knochel (Ludwig Maximilian University of Munich), Ph.D. with Gérard Cahiez (CNRS, Paris), and postdoctoral studies with Bruce Lipshutz (UC Santa Barbara, California). In Cahiez’s lab I contributed to the field of green chemistry by using non-toxic manganese and iron salts to develop green metal-catalyzed coupling reactions. In Lisphutz’s lab we co-developed with Dr. Arkady Krasovskiy (Dow Chemicals, Michigan) a modification of the Nobel Prize Wining reaction named Negishi cross-coupling, where for the first time this reaction was completed in water at room temperature in a one-pot reaction by using safe and inexpensive surfactants as micelle nano-reactors.

Selected publications :
C. Duplais, A. Krasovskiy, B. H. Lipshutz (2011). Organozinc Chemistry Enabled by Micellar Catalysis. Pd-Catalyzed Cross-Couplings Between Alkyl and Aryl Bromides in Water at Room Temperature, Organometallics, 30, 6090.

C. Duplais, A. J. Forman, B. A Baker, B. H. Lipshutz (2010). UC Pd. A New Form of Pd/C for Sonogashira Couplings. Chem. Eur. J., 16, 3366.

A. Krasovskiy, C. Duplais, B. H. Lipshutz (2009). Zn-Mediated, Pd-Catalyzed Cross-Couplings in Water at Room Temperature Without Prior Formation of Organozinc reagents J. Am. Chem. Soc., 131, 15592.

G. Cahiez, C. Duplais, J. Buendia (2009). Manganese-Catalyzed Oxydative Cross-Couplings of Grignard Reagents Using Oxygen as Oxidant. Angew. Chem. Int. Ed., 48, 6731.

G. Cahiez, A. Moyeux, J. Buendia, C. Duplais (2007). Manganese- or Iron-Catalyzed Homocoupling of Grignard Reagents Using Atmospheric Oxygen as an Oxidant, J. Am. Chem. Soc. 129, 13788.

G. Cahiez, V. Habiak, C. Duplais, A. Moyeux (2007) Iron-Catalyzed Alkylations of Aromatic Grignard Reagents, Angew. Chem. Int. Ed., 46, 4364.

C. Duplais, F. Bures, I. Sapountzis, T. J. Korn, G. Cahiez, P. Knochel (2004). An Efficient Synthesis of Diaryl Ketones by Iron-Catalyzed Arylation of Aroyl Cyanides. Angew. Chem. Int. Ed., 43, 2968.

August 2
Our article Antiplasmodial activities of dyes against Plasmodium falciparum asexual and sexual stages : Contrasted uptakes of triarylmethanes Brilliant green, Green S (E142), and Patent Blue V (E131) by erythrocytes is online International Journal for Parasitology : Drugs and Drug Resistance
L.-J. Leba, J. Popovici, Y. Estevez, S. Pelleau, E. Legrand, L. Musset, C. Duplais*

July 22
Update on my marital status, married the most amazing woman Corrie Moreau

May 11
The first paper of Caroline is online in Molecular Ecology Resources. Congrats Caro !!
C. Birer, N. Tysklind, L. Zinger*, C. Duplais*. Comparative analysis of DNA extraction methods to study the body surface microbiota of insects : a case study with ant cuticular bacteria. Mol. Ecol. Res. Early Views.

April 6
Congratulations to Caroline Birer for successfully defending her amazing and impressive Ph.D work !! Thesis title : Bacterial microbiota of ant’s cuticle in French Guiana : antibiotic activities and community ecology.
Thesis committee members : Jean-Luc Wolfender (University of Geneva), Jérôme Chave (CNRS, UMR EDB-University of Toulouse), Heidy Schimann (INRA, UMR EcoFoG), Grégory Genta-Jouve (UME COMETE-University Paris Descartes)
+ Co-PI : Bruno Figadère (CNRS, UMR BioCIS-University Paris Saclay), Lucie Zinger (ENS), Niklas Tysklind (INRA, UMR EcoFoG), Christophe Duplais (CNRS, UMR EcoFoG)

March 13
Collaborative work just published in Journal of Natural Products by Pierre Champy* & Mehdi A. Beniddir* (UMR BioCIS, Université Paris Saclay)
A. E. Fox Ramos, C. Alcover, L. Evanno, A. Maciuk, M. Litaudon, C. Duplais, G. Bernadat, J.-F. Gallard, J.-C. Jullian, E. Mouray, P. Grellier, P. M. Loiseau, S. Pomel, E. Poupon, P. Champy, M. A. Beniddir (2017). Revisiting Previously Investigated Plants : A Molecular Networking-Based Study of Geissospermum leave J. Nat. Prod. 80 (4), pp 1007–1014

March 1
You want to apply for a Ph.D co-supervised by Christophe Duplais & Corrie Moreau ? Interested in Evolution/Molecular Biology/Chemical Biology ? Interested in Ants/Bacteria/Biosynthetic Gene Clusters/Nonribosomal Peptides/Dicyclopeptides ? Please email me NOW

January 28
Check out our review with my colleague Romain Duval (IRD, UMR MERIT-Paris Descartes) just published in Natural Product Reports
R. Duval, C. Duplais (2017). Fluorescent natural products as tracers and probes in biology. Nat. Prod. Rep, 34:161-193.
AND congrats to Romain who made the beautiful Inside Front Cover

26 publications since 2007 ; 2 book chapters ; 1373 citations ; average citations per item : 52.8 ; Scopus h-index : 18

2017
L-J. Leba, J. Popovici, Y. Estevez, S. Pelleau, E. Legrand, L. Musset, C. Duplais* (2017). Contrasted antiplasmodial activities of triarylmethane analogues Brilliant Green, Green S and Patent Blue V against Plasmodium falciparum asexual and sexual stages. International Journal for Parasitology : drugs and drug resistance, 7, 314-320.

C. Birer, N. Tysklind, L. Zinger*, C. Duplais* (2017). Comparative analysis of DNA extraction protocols to assess cuticular bacterial diversity of ants. Molecular Ecology Resources, early views doi : 10.1111/1755-0998.12688

A. E. Fox Ramos, C. Alcover, L. Evanno, A. Maciuk, M. Litaudon, C. Duplais, G. Bernadat, J.-F. Gallard, J.-C. Jullian, E. Mouray, P. Grellier, P. M. Loiseau, S. Pomel, E. Poupon, P. Champy, M. A. Beniddir (2017). Revisiting Previously Investigated Plants : A Molecular Networking-Based Study of Geissospermum leave. J. Nat. Prod., 80, 1007-1014.

R. Duval*, C. Duplais (2017). Fluorescent natural products as probes and tracers in biology. Nat. Prod. Rep., 34,161-193.

2016
J. Bossu, J. Beauchêne, Y. Estevez, C. Duplais*, B. Clair* (2016). New insights on wood dimensional stability influenced by secondary metabolites : the case of a fast-growing tropical species Bagassa guianensis Aubl. PLoS ONE, 11, e0150777.

2015
L-J. Leba, L. Musset, S. Pelleau, Y. Estevez, C. Birer, S. Briolant, B. Witkowski, D. Menard, M. Delves, E. Legrand, C. Duplais, J. Popovici (2015). Use of Plasmodium falciparum culture-adapted field isolates for in vitro exflagellation-blocking assay. Malaria Journal, 14, 214.

K. Cottet, Y. Fromentin, M. Kritsanida, R. Grougnet, G. Odonne, C. Duplais, S. Michel, M.-C. Lallemand (2015). Isolation of Guttiferones from renewable parts of Symphonia globulifera by centrifugal partition chromatography Comparative. Planta Med., 81, 1606.

2014
K. Cottet, G. Genta-Jouve, Y. Fromentin, G. Odonne, C. Duplais, O. Laprevote, S. Michel, M.-C. Lallemand (2014). Comparative LC-MS-based metabolite profiling of the ancient tropical rainforest tree Symphonia globulifera. Phytochemistry, 108, 102.

2013
T. M. Casella, V. Eparvier, H. Mandavad, A. Bendelac, G. Odonne, C. Duplais, L. S. Espindola, D. Stien (2013). Antimicrobial and cytotoxic secondary metabolites from tropical leaf endophytes : Isolation of antibacterial agent pyrrocidine C from Lewia infectoria SNB-GTC2402. Phytochemistry, 96, 370.

2012
B. H. Lipshutz, B. R. Taft, A. R. Abela, S. Ghorai, A. Krasovskiy, C. Duplais (2012). Catalysis in the Service of Green Chemistry : Nobel Prize-Winning Palladium-Catalyzed Cross-Couplings, Run in Water at Room Temperature. Platinium Metals Rev., 56, 64.

2011
C. Duplais, A. Krasovskiy, B. H. Lipshutz (2011). Organozinc Chemistry Enabled by Micellar Catalysis. Pd-Catalyzed Cross-Couplings Between Alkyl and Aryl Bromides in Water at Room Temperature. Organometallics, 30, 6090.

B. H. Lipshutz, S. Ghorai, A. R. Abela, R. Moser, T. Nishikata, C. Duplais, A. Krasovskiy, R. D. Gaston, R. C. Gadwood (2011). TPGS-750-M : A Second-Generation Amphiphile for Metal-Catalyzed Cross-Couplings in Water at Room Temperature. J. Org. Chem., 76, 4379.

A. Krasovskiy, I. Thomé, J. Graff, V. Krasovskaya, P. Konopelski, C. Duplais, B. H. Lipshutz, (2011). Cross-Couplings of Alkyl Halides with Heteroaromatic Halides, in Water at Room Temperature. Tetrahedron Lett., 52, 2203.

2010
A. Krasovskiy, C. Duplais, B. H. Lipshutz (2010). Stereoselective Negishi-like Couplings Between Alkenyl and Alkyl Halides in Water at Room Temperature. Org. Lett., 12, 4742.

B. H. Lipshutz, A. R. Abela, Z. V. Boskovic, T. Nishikata, C. Duplais, A. Krasovskiy (2010). Greening Up : Cross-Coupling Chemistry. Top. Catal., 53, 985.

C. Duplais, A. J. Forman, B. A Baker, B. H. Lipshutz (2010). UC Pd. A New Form of Pd/C for Sonogashira Couplings. Chem. Eur. J., 16, 3366.

C. Duplais, A. Krasovskiy, Alina Wattenberg, B. H. Lipshutz (2010). Cross-Couplings Between Benzylic and Aryl Halides ‘‘on Water.’’ Synthesis of Diarylmethanes. Chem. Commun., 562.

2009
A. Krasovskiy, C. Duplais, B. H. Lipshutz (2009). Zn-Mediated, Pd-Catalyzed Cross-Couplings in Water at Room Temperature Without Prior Formation of Organozinc reagents. J. Am. Chem. Soc., 131, 15592.

G. Cahiez, C. Duplais, J. Buendia (2009). The Chemistry of Organomanganese Compounds. Chem. Rev., 109, 1434.

G. Cahiez, C. Duplais, J. Buendia (2009). Manganese-Catalyzed Oxydative Cross-Couplings of Grignard Reagents Using Oxygen as Oxidant. Angew. Chem. Int. Ed., 48, 6731.

G. Cahiez, C. Chaboche, C. Duplais, A. Moyeux (2009). A New Efficient Catalytic System for the Chemoselective Cobalt-Catalyzed Cross-Coupling of Aryl Grignard Reagents with Primary and Secondary Alkyl Bromides. Org. Lett., 11, 277.

2008
G. Cahiez, C. Chaboche, C. Duplais, A. Gulianni, A. Moyeux (2008) Cobalt-Catalyzed Cross Coupling Reaction Between Functionnalized Primary and Secondary Alkyl Halides and Aliphatic Grignard Reagents. Adv. Synth. Catal. 350, 1484.

2007
G. Cahiez, A. Moyeux, J. Buendia, C. Duplais (2007). Manganese- or Iron-Catalyzed Homocoupling of Grignard Reagents Using Atmospheric Oxygen as an Oxidant. J. Am. Chem. Soc., 129, 13788.

G. Cahiez, C. Duplais, A. Moyeux (2007). Iron-Catalyzed Alkylation of Alkenyl Grignard Reagents. Org. Lett., 9, 3253.

G. Cahiez, V. Habiak, C. Duplais, A. Moyeux (2007). Iron-Catalyzed Alkylations of Aromatic Grignard Reagents. Angew. Chem. Int. Ed., 46, 4364.

2004
C. Duplais, F. Bures, I. Sapountzis, T. J. Korn, G. Cahiez, P. Knochel (2004). An Efficient Synthesis of Diaryl Ketones by Iron-Catalyzed Arylation of Aroyl Cyanides. Angew. Chem. Int. Ed., 43, 2968.

Positions
2016- Present
CNRS Chargé de Recherche first class (CR1) at EcoFoG
Scientific affiliate at the Field Museum of Chicago. Corrie Moreau Lab
Oct. 2011 - 2016
CNRS Chargé de Recherche (CR2) - research scientist (group leader) at EcoFoG, Cayenne, French Guiana, France.
2011 CNRS job application N°16/05 (natural products, chemical ecology), rank : 1
2011 CNRS job application N°12/03 (organic chemistry, catalysis), rank : 1
2011
Postdoctoral Fellow, University of Paris XIII, France
Department of Chemistry, PI : Gérard Cahiez (CNRS).
2008 - 2011
Postdoctoral Fellow, University of California, Santa Barbara, USA
Department of Chemistry and Biochemistry, PI : Bruce Lipshutz.

Education
2016
HDR (Habilitation à Diriger des Recherches) – University of French Guiana (France)
Medicinal chemistry against malaria and chemical ecology in French Guiana.
2004 - 2008
Ph.D. – University of Cergy-Pontoise (France)
Manganese- and iron-catalyzed cross-coupling reactions and preparation of functionalized organomanganese compounds. Advisor : Gérard Cahiez, (CNRS).
2003 - 2004
M.Sc. – University of Cergy-Pontoise (France) ; Ludwig Maximilian University of Munich (Germany)
Fine organic chemistry and total synthesis. Master’s thesis project on iron catalysis. Advisors : Gérard Cahiez (CNRS) and Paul Knochel (LMU, Munich)
2001 - 2004
Engineer school in organic and inorganic chemistry (ESCOM, Cergy-Pontoise, France)